2021 season
23 January 2022: Bills at Chiefs

2021 Season Divisional Playoff
16 January 2022: Patriots at Bills

2021 Season Wildcard Playoff
09 January 2022: Jets at Bills

Week 18
02 January 2022: Falcons at Bills

Week 17
26 December 2021: Bills at Patriots

Week 16
19 December 2021: Panthers at Bills

Week 15
12 December 2021: Bills at Buccaneers

Week 14
06 December 2021: Patriots at Bills

Week 13
25 November 2021: Bills at Saints

Week 12
21 November 2021: Colts at Bills

Week 11
14 November 2021: Bills at Jets

Week 10
07 November 2021: Bills at Jaguars

Week 9
31 October 2021: Dolphins at Bills

Week 8
18 October 2021: Bills at Titans

Week 6
10 October 2021: Bills at Chiefs

Week 5
03 October 2021: Texans at Bills

Week 4
26 September 2021: WFT at Bills

Week 3
19 September 2021: Bills at Dolphins

Week 2
12 September 2021: Steelers at Bills

Week 1